Category Archives: Uncategorized

Opening: PhD student (m/f/d) in Biophysics

The Hyman and Zechner labs are looking for a PhD student to research the control of cellular noise via phase separation. Brief summary: Liquid condensates provide a potential mechanism to control molecular fluctuations in cells. We have recently provided a first proof of principle of this idea using theory and single-cell experiments. In this project, […]

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The National Academy of Sciences elected new members…

and we are happy that Tony got elected as well! Congratulations from the whole lab. The Academy has around 2400 members amd Tony will be one of only 500 international Scientist in the Academy. The National Academy of Sciences was founded in 1863 to “…provide independent, objective advice to the nation on matters related to […]

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Tony wins NOMIS award and is now NOMIS distinguished scientist

The Swiss based NOMIS foundation “…enables outstanding talent to take on high-risk research”. Now they awarded Tony and the lab $2.5 million in recognition of our “contributions to the advancement of science and human progress”. The money is awarded for the project “Phase Transitions and Biological Condensates: An Important New Paradigm for Understanding Disease,” and […]

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Die neue Biologie der Tröpfchen

Berlin newspaper Tagesspiegel article of Sascha Karberg about the discovery and applications of phase separation “Es ist eine Entdeckung, die das Verständnis der Zelle revolutioniert. Die erste Firma, die das neue Wissen für neue Therapien nutzt, kommt nun nach Berlin”. click here for full article in german

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Our kinetochore paper is selected for the 65th birthday collection of JCB

For the collection celebrating the 65th anniversary of the Journal of Cell biology, our paper Functional Analysis of Kinetochore Assembly in Caenorhabditis elegans was selected for its contribution to “dissecting the mechanics of cell division”. The paper from 2001 by Karen and Arshad, postdocs in our lab at the time has great company there. Click […]

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Tony wins 2020 Wiley Prize in Biomolecular Sciences

Tony wins the 19th annual prize together with Clifford Brangwynne of Princeton university and Michael Rosen of the Southwestern University in Texas for their work on defining phase-separated biomolecular condensates. In a statement of the Wiley foundation their work was recognized for… “revealing a new principle for subcellular compartmentalization based on formation of phase-separated biomolecular […]

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Enrichment of soluble tubulin at centrosomes

Recent work from Dresden (2017) suggests that centrosomes are condensates that nucleate in part by concentrating soluble tubulin. Here we show that indeed tubulin is extremely concentrated at centrosome in C. elegans embryos, suggesting that such a tubulin concentration could indeed play a key role in nucleation. References 1-https://www.ncbi.nlm.nih.gov/pubmed/28575670 2-https://www.ncbi.nlm.nih.gov/pubmed/31636117

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Tony wins Carl Zeiss lecture award

The award to Tony comes from the German Society for Cell Biology for excellent achievements in research and was established in 1990 by the company Zeiss. Tony will lecture on September 27th in Tübingen during the fall conference of the German Society for Biochemistry and Molecular Biology (GBM) and the German Society for Cell Biology […]

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Small molecules that dissolve stress granules

In ALS, a mutated nuclear protein, FUS (fused in sarcoma), mislocalises to the cytoplasm and aggregates in stress granules. This leads to a liquid to solid transition of the granules and a consequent degeneration of the motor neuron (motor neuron die-back ). We show that lipoamide and lipoic acid can prevent the aggregation of FUS and consequently […]

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Suzanne Eaton

We, past and current members of the Hyman lab, are reeling from the sudden and tragic loss of Suzanne Eaton. She was a wonderful person who lives on in our hearts. In this difficult time, we stand together with her family and colleagues. https://www.mpi-cbg.de/suzanne-eaton/

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  • Selected Videos


    iBio video about P granule formation


    An interview with Tony about Phase Transitions and Disease


    Phase separation in cell polarity: Saha et al, Cell 2016


    Encouraging Innovation, iBiology.org


    The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016


    Cell PaperFlick on Phase Transitions in Disease


    Check out this playlist to watch all the videos in our "Two Minute Talk" Series


    Ways of Growing, a film created for the MitoSys Project


    What is a Discovery?


    Embryonic Development of C.elegans