Recent work from Dresden (2017) suggests that centrosomes are condensates that nucleate in part by concentrating soluble tubulin. Here we show that indeed tubulin is extremely concentrated at centrosome in C. elegans embryos, suggesting that such a tubulin concentration could indeed play a key role in nucleation. References 1-https://www.ncbi.nlm.nih.gov/pubmed/28575670 2-https://www.ncbi.nlm.nih.gov/pubmed/31636117
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(1/2) Proud to share my preprint on concentration buffering in multi-component systems by LLPS https://www.biorxiv.org/content/10.1101/2021.01.05.425486v1. We show that buffering occurs only if the molecular interactions among the phase-separating proteins are related to their expression noise in a specific manner.
