Author Archives: Mohamad Almedawar

The Hyman lab bids Amayra farewell

Amayra Hernández-Vega concluded a 6-year service in the Hyman Lab this November as a postdoc, with an impressive track record of publications and scientific outreach. Amayra’s farewell had to be done in compliance with Coronavirus-safety measures, but a bigger celebration is planned when the pandemic eases up. Amayra, we wish you a smooth start in Barcelona […]

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Tony receives the 2021 HFSP Nakasone Award

The 2021 HFSP Nakasone Award recognises Tony and Cliff for the discovery of a new state of biological matter, namely, liquid-liquid phase separation. Since 2009, the Hyman and Brangwynne labs have observed biomolecular condensation in various cell types and organisms and have helped to determine their functions in physiological and pathological conditions. Congratulations to the […]

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The Hyman lab welcomes Alexandra, Arsenii, MJ, and Peter

The Hyman lab recently recruited new members in different positions. PhD Students Alexandra Sergeeva is starting as a PhD student in the Hyman and Alberti Labs. The MPI-CBG has initiated rolling admissions for prospective PhD students who can apply through the IMPRS-CellDevoSys portal. Masters Students Arsenii Dmitriev is a Masters Student at the TU Dresden. […]

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Lab retreat in Freital – September 28th, 2020

The Hyman Lab held a 1-day-retreat at Schloss Burgk in Freital, Germany, to look back at progress made since last year, how the field of phase separation is taking shape, and the way forward from here. Some impressions from the day:

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The Postdoc Summer Chalk Talks 2020 continue with Patrick McCall and Samir Vaid

Chalk Talk announcement - Patrick and Samir - August 2020

Even though it’s 35°C outside and the wasp season is in full swing, a sizeable group of scientists gathered outside the entrance of the MPI-CBG to listen to Patrick McCall and Samir Vaid walk them through their research interests and outcomes in the second week of our summer chalk talk series. Patrick McCall, an ELBE […]

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Postdoc Summer Chalk Talks 2020 take off with Tina and Thomas

Keeping in mind social distancing rules while ensuring a relaxed and informal setting, Tina, Jacobo, and Anna launched the Postdoc Summer Chalk Talks 2020 at the MPI-CBG to offer a weekly Friday seminar during the summer holidays. In the first round, Tina Wiegend from the Hyman & Grill Labs, and Thomas Quail from the Brugués […]

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Opening: PhD student (m/f/d) in Biophysics

The Hyman and Zechner labs are looking for a PhD student to research the control of cellular noise via phase separation. Brief summary: Liquid condensates provide a potential mechanism to control molecular fluctuations in cells. We have recently provided a first proof of principle of this idea using theory and single-cell experiments. In this project, […]

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Enrichment of soluble tubulin at centrosomes

Recent work from Dresden (2017) suggests that centrosomes are condensates that nucleate in part by concentrating soluble tubulin. Here we show that indeed tubulin is extremely concentrated at centrosome in C. elegans embryos, suggesting that such a tubulin concentration could indeed play a key role in nucleation. References 1-https://www.ncbi.nlm.nih.gov/pubmed/28575670 2-https://www.ncbi.nlm.nih.gov/pubmed/31636117

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Small molecules that dissolve stress granules

In ALS, a mutated nuclear protein, FUS (fused in sarcoma), mislocalises to the cytoplasm and aggregates in stress granules. This leads to a liquid to solid transition of the granules and a consequent degeneration of the motor neuron (motor neuron die-back ). We show that lipoamide and lipoic acid can prevent the aggregation of FUS and consequently […]

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  • Selected Videos


    iBio video about P granule formation


    An interview with Tony about Phase Transitions and Disease


    Phase separation in cell polarity: Saha et al, Cell 2016


    Encouraging Innovation, iBiology.org


    The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016


    Cell PaperFlick on Phase Transitions in Disease


    Check out this playlist to watch all the videos in our "Two Minute Talk" Series


    Ways of Growing, a film created for the MitoSys Project


    What is a Discovery?


    Embryonic Development of C.elegans