Hyman Lab News
Phase separation buffers noise in cells
In collaboration with the Zechner and Jülicher groups, we now show in theory and experiments that liquid-liquid phase separation (LLPS) can be a very effective mechanism to buffer protein concentrations against gene expression noise.
Rheology of protein condensates using optical traps
Louise and her coworkers now developed a novel method based on optical traps to study the frequency-dependent rheology and the surface tension of P-granule protein PGL-3 condensates as a function of salt concentration.
How do you choose a research topic?
Choosing a research topic is an important decision at any level. The choice shapes decisions about what graduate lab to join, which post-doctoral position to pursue, how to start an independent lab, and what companies might make good employers.
Phase Transitions form Virus Replication Compartments in Cells
Former postdoc Zoltan worked with the Whelan lab on VSV (Vesicular Stomatitis Virus). They show liquid-liquid phase separation (LLPS) seems to play an important role in host-pathogen interactions.
Former postdoc Richard opens his own lab in Oxford
Congratulations to Richard! Check out his website.
We are organizing an EMBO Practical Course for studying phase separation in biology!
This course will provide high quality instruction in the physical chemistry theories underlying biological phase separation, followed by hands on practical training in the assays and cutting-edge techniques used in this emerging field.