2024

• Solutes unmask differences in clustering versus phase separation of FET proteins

  research article

  Mrityunjoy Kar, Laura T Vogel, Gaurav Chauhan, Suren Felekyan, Hannes Ausserwöger, Timothy J Welsh, Furqan Dar, Anjana R Kamath, Tuomas PJ Knowles, Anthony A Hyman, Claus AM Seidel, Rohit V Pappu

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  PDF

• Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

  bioRxiv

  open access

  research article

  Xiao Yan, David Kuster, Priyesh Mohanty, Jik Nijssen, Karina Pombo-García, Azamat Rizuan, Titus M. Franzmann, Aleksandra Sergeeva, Patricia M. Passos, Leah George, Szu-Huan Wang, Jayakrishna Shenoy, Helen L. Danielson, Alf Honigmann, Yuna M. Ayala, Nicolas L. Fawzi, Jeetain Mittal, Simon Alberti, Anthony A. Hyman. bioRxiv 2024.01.23.576837

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2023

• CD-CODE: crowdsourcing condensate database and encyclopedia

  open access

  research article

  Rostam N, Ghosh S, Chow CF, Hadarovich A, Landerer C, Ghosh R, Moon H, Hersemann L, Mitrea DM, Klein IA, Hyman AA. Nature Methods. 2023 May;20(5):673-6.

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• Molecular mechanisms of stress-induced reactivation in mumps virus condensates

  open access

  research article

  Zhang X, Sridharan S, Zagoriy I, Eugster Oegema C, Ching C, Pflaesterer T, Fung HKH, Becher I, Poser I, Müller CW, Hyman AA, Savitski MM, Mahamid J.Cell. 2023 Apr 27;186(9):1877-1894.e27.

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2022

• SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

  open access

  research article

  Maharana S, Kretschmer S, Hunger S, Yan X, Kuster D, Traikov S, Zillinger T, Gentzel M, Elangovan S, Dasgupta P, Chappidi N, Lucas N, Maser KI, Maatz H, Rapp A, Marchand V, Chang YT, Motorin Y, Hubner N, Hartmann G, Hyman AA, Alberti S, Lee-Kirsch MA.Mol Cell. 2022 Oct 6;82(19):3712-3728.e10.

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• Adaptation to environmental temperature in divergent clades of the nematode Pristionchus pacificus

  open access

  research article

  Leaver M, Moreno E, Kayhan M, McGaughran A, Rödelsperger C, Sommer RJ, Hyman AA. Evolution. 2022 Aug 1;76(8):1660-73.

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• Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions

  open access

  research article

  Kar M, Dar F, Welsh TJ, Vogel LT, Kühnemuth R, Majumdar A, Krainer G, Franzmann TM, Alberti S, Seidel CA, Knowles TP. Proceedings of the National Academy of Sciences. 2022 Jul 12;119(28):e2202222119.

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• Sequence-dependent surface condensation of a pioneer transcription factor on DNA

  open access

  research article

  Morin JA, Wittmann S, Choubey S, Klosin A, Golfier S, Hyman AA, Jülicher F, Grill SW. Nature Physics. 2022 Mar;18(3):271-6.

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• Molecular mechanism of stress-induced reactivation in mumps virus condensates

  open access

  research article

  Zhang X, Sridharan S, Zagoriy I, Oegema CE, Ching C, Pflaesterer T, Fung HK, Poser I, Müller CW, Hyman AA, Savitski MM. Biophysical Journal. 2022 Feb 11;121(3):148a.

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2021

• Glycine-rich peptides from FUS have an intrinsic ability to self-assemble into fibers and networked fibrils

  open access

  research article

  Kar M, Posey AE, Dar F, Hyman AA, Pappu RV. Biochemistry. 2021 Oct 14;60(43):3213-22.

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• Quantitative theory for the diffusive dynamics of liquid condensates

  open access

  research article

  Hubatsch L, Jawerth LM, Love C, Bauermann J, Tang TD, Bo S, Hyman AA, Weber CA. Elife. 2021 Oct 12;10:e68620.

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• Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates

  open access

  research article

  Fritsch AW, Diaz-Delgadillo AF, Adame-Arana O, Hoege C, Mittasch M, Kreysing M, Leaver M, Hyman AA, Jülicher F, Weber CA. Proceedings of the National Academy of Sciences. 2021 Sep 14;118(37):e2102772118.

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• HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain

  open access

  research article

  Boczek EE, Fürsch J, Niedermeier ML, Jawerth L, Jahnel M, Ruer-Gruß M, Kammer KM, Heid P, Mediani L, Wang J, Yan X. Elife. 2021 Sep 6;10:e69377.

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• Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo

  open access

  research article

  Jang S, Xuan Z, Lagoy RC, Jawerth LM, Gonzalez IJ, Singh M, Prashad S, Kim HS, Patel A, Albrecht DR, Hyman AA. Biophysical journal. 2021 Apr 6;120(7):1170-86.

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• Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

  review

  Alberti S, Hyman AA. Nature reviews Molecular cell biology. 2021 Mar;22(3):196-213.

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• Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

  open access

  research article

  Krainer G, Welsh TJ, Joseph JA, St George-Hyslop P, Hyman AA, Collepardo-Guevara R, Alberti S, Knowles TP. Biophysical Journal. 2021 Feb 12;120(3):28a.

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• ESI mutagenesis: a one-step method for introducing mutations into bacterial artificial chromosomes

  open access

  research article

  Rondelet A, Pozniakovsky A, Namboodiri D, Da Silva RC, Singh D, Leuschner M, Poser I, Ssykor A, Berlitz J, Schmidt N, Röhder L. Life science alliance. 2021 Feb 1;4(2).

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2020

• ASCB Keith Porter Lecture

  essay

  open access

  Hyman AA. Molecular biology of the cell. 2020 Dec 15;31(26):2864-7.

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• Drops and fibers—how biomolecular condensates and cytoskeletal filaments influence each other

  open access

  review

  Wiegand T, Hyman AA. Emerging topics in life sciences. 2020 Dec 12;4(3):247.

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• Protein condensates as aging Maxwell fluids

  open access

  research article

  Jawerth L, Fischer-Friedrich E, Saha S, Wang J, Franzmann T, Zhang X, Sachweh J, Ruer M, Ijavi M, Saha S, Mahamid J. Science. 2020 Dec 11;370(6522):1317-23.

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• Erratum: Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical Traps [Phys. Rev. Lett. 121, 258101 (2018)]

  open access

  research article

  Jawerth LM, Ijavi M, Ruer M, Saha S, Jahnel M, Hyman AA, Jülicher F, Fischer-Friedrich E. Physical Review Letters. 2020 Nov 23;125(22):229901.

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• Generalized models for bond percolation transitions of associative polymers

  research article

  Choi JM, Hyman AA, Pappu RV. Physical Review E. 2020 Oct 6;102(4):042403.

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• Partitioning of cancer therapeutics in nuclear condensates

  open access

  research article

  Klein IA, Boija A, Afeyan LK, Hawken SW, Fan M, Dall'Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR, Sagi I. Science. 2020 Jun 19;368(6497):1386-92.

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• Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

  open access

  research article

  Iserman C, Altamirano CD, Jegers C, Friedrich U, Zarin T, Fritsch AW, Mittasch M, Domingues A, Hersemann L, Jahnel M, Richter D. Cell. 2020 May 14;181(4):818-31.

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• RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation

  open access

  research article

  Guillén-Boixet J, Kopach A, Holehouse AS, Wittmann S, Jahnel M, Schlüßler R, Kim K, Trussina IR, Wang J, Mateju D, Poser I. Cell. 2020 Apr 16;181(2):346-61.

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• Phase separation provides a mechanism to reduce noise in cells

  research article

  Klosin A, Oltsch F, Harmon T, Honigmann A, Jülicher F, Hyman AA, Zechner C. Science. 2020 Jan 24;367(6476):464-8.

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2019

• Soluble tubulin is significantly enriched at mitotic centrosomes

  open access

  research article

  Baumgart J, Kirchner M, Redemann S, Bond A, Woodruff J, Verbavatz JM, Jülicher F, Müller-Reichert T, Hyman AA, Brugués J. Journal of Cell Biology. 2019 Dec 2;218(12):3977-85.

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• Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

  open access

  research article

  Siahaan V, Krattenmacher J, Hyman AA, Diez S, Hernández-Vega A, Lansky Z, Braun M. Nature cell biology. 2019 Sep;21(9):1086-92.

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• FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

  open access

  research article

  Marrone L, Drexler HC, Wang J, Tripathi P, Distler T, Heisterkamp P, Anderson EN, Kour S, Moraiti A, Maharana S, Bhatnagar R. Acta neuropathologica. 2019 Jul 1;138:67-84.

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• Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.

  open access

  research article

  Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M. The EMBO journal. 2019 Jan 15;38(2):e99876.

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• Publisher Correction: Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding

  open access

  research article

  Stewart MP, Helenius J, Toyoda Y, Ramanathan SP, Muller DJ, Hyman AA. Nature. 2019;571(7764):E5-.

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2018

• Salt-dependent rheology and surface tension of protein condensates using optical traps

  research article

  Jawerth LM, Ijavi M, Ruer M, Saha S, Jahnel M, Hyman AA, Jülicher F, Fischer-Friedrich E. Physical review letters. 2018 Dec 18;121(25):258101.

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• Phase transitions drive the formation of vesicular stomatitis virus replication compartments

  open access

  research article

  Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SP. MBio. 2018 Nov 7;9(5):10-128.

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• A user's guide for phase separation assays with purified proteins

  open access

  research article

  Alberti S, Saha S, Woodruff JB, Franzmann TM, Wang J, Hyman AA. Journal of molecular biology. 2018 Nov 2;430(23):4806-20.

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• Positioning of Particles in Active Droplets

  research article

  Zwicker D, Baumgart J, Redemann S, Müller-Reichert T, Hyman AA, Jülicher F. Physical review letters. 2018 Oct 12;121(15):158102.

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• The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion

  open access

  research article

  Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van Der Lelij P, Kreidl E. The EMBO journal. 2018 Aug 1;37(15):e97150.

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• A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins

  open access

  research article

  Wang J, Choi JM, Holehouse AS, Lee HO, Zhang X, Jahnel M, Maharana S, Lemaitre R, Pozniakovsky A, Drechsel D, Poser I. Cell. 2018 Jul 26;174(3):688-99.

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• Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery

  open access

  research article

  Kroschwald S, Munder MC, Maharana S, Franzmann TM, Richter D, Ruer M, Hyman AA, Alberti S. Cell reports. 2018 Jun 12;23(11):3327-39.

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• Controlling compartmentalization by non-membrane-bound organelles

  open access

  review

  Wheeler RJ, Hyman AA. Philosophical Transactions of the Royal Society B: Biological Sciences. 2018 May 26;373(1747):20170193.

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• RNA buffers the phase separation behavior of prion-like RNA binding proteins

  open access

  research article

  Maharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M. Science. 2018 May 25;360(6391):918-21.

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• Tau protein liquid-liquid phase separation can initiate tau aggregation

  open access

  research article

  Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C. The EMBO journal. 2018 Apr 3;37(7):e98049.

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• Protein dynamics in complex DNA lesions

  open access

  research article

  Aleksandrov R, Dotchev A, Poser I, Krastev D, Georgiev G, Panova G, Babukov Y, Danovski G, Dyankova T, Hubatsch L, Ivanova A. Molecular cell. 2018 Mar 15;69(6):1046-61.

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• Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria

  open access

  research article

  Hsu F, Spannl S, Ferguson C, Hyman AA, Parton RG, Zerial M. Elife. 2018 Feb 22;7:e32282.

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• Isogenic FUS-eGFP iPSC reporter lines enable quantification of FUS stress granule pathology that is rescued by drugs inducing autophagy

  open access

  research article

  Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey U, Hyman AA, Sterneckert JL. Stem cell reports. 2018 Feb 13;10(2):375-89.

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• Organization and function of non-dynamic biomolecular condensates

  review

  Woodruff JB, Hyman AA, Boke E. Trends in biochemical sciences. 2018 Feb 1;43(2):81-94.

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  PDF

• Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

  open access

  research article

  Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A. Nature communications. 2018 Jan 23;9(1):335.

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• Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

  open access

  research article

  Enos SJ, Dressler M, Gomes BF, Hyman AA, Woodruff JB. Biology Open. 2018 Jan 15;7(1):bio029777.

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• Phase separation of a yeast prion protein promotes cellular fitness

  open access

  research article

  Franzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nüske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA. Science. 2018 Jan 5;359(6371):eaao5654.

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2017

• Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding

  open access

  research article

  Toyoda Y, Cattin CJ, Stewart MP, Poser I, Theis M, Kurzchalia TV, Buchholz F, Hyman AA, Müller DJ. Nature communications. 2017 Nov 2;8(1):1266.

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• Local nucleation of microtubule bundles through tubulin concentration into a condensed tau phase

  open access

  research article

  Hernández-Vega A, Braun M, Scharrel L, Jahnel M, Wegmann S, Hyman BT, Alberti S, Diez S, Hyman AA. Cell reports. 2017 Sep 5;20(10):2304-12.

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• Molecular biology: A liquid reservoir for silent chromatin

  commentary

  open access

  review

  Klosin A, Hyman AA. Nature. 2017 Jul 13;547(7662):168-9.

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• An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

  open access

  research article

  review

  Mateju D, Franzmann TM, Patel A, Kopach A, Boczek EE, Maharana S, Lee HO, Carra S, Hyman AA, Alberti S. The EMBO journal. 2017 Jun 14;36(12):1669-87.

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• The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin

  open access

  research article

  Woodruff JB, Gomes BF, Widlund PO, Mahamid J, Honigmann A, Hyman AA. Cell. 2017 Jun 1;169(6):1066-77.

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• Stem cells: the new "model organism"

  open access

  perspective

  Drubin DG, Hyman AA. Molecular biology of the cell. 2017 Jun 1;28(11):1409-11.

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• ATP as a biological hydrotrope

  research article

  Patel A, Malinovska L, Saha S, Wang J, Alberti S, Krishnan Y, Hyman AA. Science. 2017 May 19;356(6339):753-6.

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  PDF

• Biomolecular condensates: organizers of cellular biochemistry

  review

  Banani SF, Lee HO, Hyman AA, Rosen MK. Nature reviews Molecular cell biology. 2017 May;18(5):285-98.

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  PDF

• Growth and division of active droplets provides a model for protocells

  open access

  research article

  Zwicker D, Seyboldt R, Weber CA, Hyman AA, Jülicher F. Nature Physics. 2017 Apr;13(4):408-13.

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2016

• In vitro reconstitution of a membrane switch mechanism for the polarity protein LGL

  research article

  Visco I, Hoege C, Hyman AA, Schwille P. Journal of Molecular Biology. 2016 Dec 4;428(24):4828-42.

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• The mitotic spindle in the one-cell C. elegans embryo is positioned with high precision and stability

  open access

  research article

  Pecreaux J, Redemann S, Alayan Z, Mercat B, Pastezeur S, Garzon-Coral C, Hyman AA, Howard J. Biophysical Journal. 2016 Oct 18;111(8):1773-84.

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• Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

  open access

  research article

  Wueseke O, Zwicker D, Schwager A, Wong YL, Oegema K, Jülicher F, Hyman AA, Woodruff JB. Biology open. 2016 Oct 15;5(10):1431-40.

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• Are aberrant phase transitions a driver of cellular aging?

  open access

  perspective

  Alberti S, Hyman AA. BioEssays. 2016 Oct;38(10):959-68.

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• Polar positioning of phase-separated liquid compartments in cells regulated by an mRNA competition mechanism

  open access

  research article

  Saha S, Weber CA, Nousch M, Adame-Arana O, Hoege C, Hein MY, Osborne-Nishimura E, Mahamid J, Jahnel M, Jawerth L, Pozniakovski A. Cell. 2016 Sep 8;166(6):1572-84.

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• Common molecular pathways in amyotrophic lateral sclerosis and frontotemporal dementia

  review

  Weishaupt JH, Hyman T, Dikic I. Trends in molecular medicine. 2016 Sep 1;22(9):769-83.

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  PDF

• A locus in Pristionchus pacificus that is responsible for the ability to give rise to fertile offspring at higher temperatures

  open access

  research article

  Leaver M, Kienle S, Begasse ML, Sommer RJ, Hyman AA. Biology Open. 2016 Aug 15;5(8):1111-7.

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• Rheology of the active cell cortex in mitosis

  open access

  research article

  Fischer-Friedrich E, Toyoda Y, Cattin CJ, Müller DJ, Hyman AA, Jülicher F. Biophysical journal. 2016 Aug 9;111(3):589-600.

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• Amyloid-like self-assembly of a cellular compartment

  open access

  research article

  Boke E, Ruer M, Wühr M, Coughlin M, Lemaitre R, Gygi SP, Alberti S, Drechsel D, Hyman AA, Mitchison TJ. Cell. 2016 Jul 28;166(3):637-50.

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• Priority of discovery in the life sciences

  open access

  opinion

  Vale RD, Hyman AA. Elife. 2016 Jun 16;5:e16931.

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• TransgeneOmics - a transgenic platform for protein localization based function exploration

  open access

  review

  Hasse S, Hyman AA, Sarov M. Methods. 2016 Mar 1;96:69-74.

  Read

• Visualizing the molecular sociology at the HeLa cell nuclear periphery

  research article

  Mahamid J, Pfeffer S, Schaffer M, Villa E, Danev R, Kuhn Cuellar L, Förster F, Hyman AA, Plitzko JM, Baumeister W. Science. 2016 Feb 26;351(6276):969-72.

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2015

• A human interactome in three quantitative dimensions organized by stoichiometries and abundances

  open access

  research article

  Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA. Cell. 2015 Oct 22;163(3):712-23.

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• A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation

  open access

  research article

  Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A. Cell. 2015 Aug 27;162(5):1066-77.

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• Emergent properties of the metaphase spindle

  open access

  review

  Reber S, Hyman AA. Cold Spring Harbor perspectives in biology. 2015 Jul 1;7(7):a015784.

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• Regulated assembly of a supramolecular centrosome scaffold in vitro

  open access

  research article

  Woodruff JB, Wueseke O, Viscardi V, Mahamid J, Ochoa SD, Bunkenborg J, Widlund PO, Pozniakovsky A, Zanin E, Bahmanyar S, Zinke A. Science. 2015 May 15;348(6236):808-12.

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• Temperature dependence of cell division timing accounts for a shift in the thermal limits of C. elegans and C. briggsae

  open access

  research article

  Begasse ML, Leaver M, Vazquez F, Grill SW, Hyman AA. Cell reports. 2015 Feb 10;10(5):647-53.

  Read

• Method: In vitro analysis of pericentriolar material assembly

  research article

  Woodruff JB, Hyman AA. Methods in cell biology. 2015 Jan 1 (Vol. 129, pp. 369-382). Academic Press.

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  PDF

2014

• The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix

  open access

  research article

  Wueseke O, Bunkenborg J, Hein MY, Zinke A, Viscardi V, Woodruff JB, Oegema K, Mann M, Andersen JS, Hyman AA. Molecular Biology of the Cell. 2014 Oct 10;25(19):2984.

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• Liquid-liquid phase separation in biology

  open access

  review

  Hyman AA, Weber CA, Jülicher F. Annual review of cell and developmental biology. 2014 Oct 6;30:39-58.

  Read

• Pericentriolar material structure and dynamics

  open access

  review

  Woodruff JB, Wueseke O, Hyman AA. Philosophical Transactions of the Royal Society B: Biological Sciences. 2014 Sep 5;369(1650):20130459.

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• Quantification of surface tension and internal pressure generated by single mitotic cells

  open access

  research article

  Fischer-Friedrich E, Hyman AA, Jülicher F, Müller DJ, Helenius J. Scientific reports. 2014 Aug 29;4(1):6213.

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• Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival

  open access

  research article

  Toyoda Y, Erkut C, Pan-Montojo F, Boland S, Stewart MP, Müller DJ, Wurst W, Hyman AA, Kurzchalia TV. Biology open. 2014 Jul 25;3(8):777-84.

  Read

• Encouraging innovation

  open access

  opinion

  Mol Biol Cell. 2014 Feb;25(4):427-8.

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2013

• Principles of PAR polarity in Caenorhabditis elegans embryos

  opinion

  review

  Hoege C, Hyman AA. Nature reviews Molecular cell biology. 2013 May;14(5):315-22.

  Read

  PDF

• Funding innovative science

  open access

  opinion

  Hyman AA. Science. 2013 Jan 11;339(6116):119-.

  Read

2012

• In retrospect: the origin of life

  essay

  open access

  Hyman AA, Brangwynne C. Nature. 2012 Nov;491, 524-525

  Read

• Beyond oil and water — phase transitions in cells

  open access

  perspective

  Hyman AA, Simons K. Science. 2012 Aug 31;337(6098):1047-9.

  Read

• Organelle growth control through limiting pools of cytoplasmic components

  open access

  review

  Goehring NW, Hyman AA. Current Biology. 2012 May 8;22(9):R330-9.

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2011

• Whither systems biology

  open access

  opinion

  Hyman AA. Philosophical Transactions of the Royal Society B: Biological Sciences. 2011 Dec 27;366(1584):3635-7.

  Read

• Samurai sword sets spindle size

  open access

  review

  Reber S, Hyman AA. Cell. 2011 Dec 9;147(6):1224-5.

  Read

• Beyond HeLa cells

  commentary

  open access

  Hyman AH, Simons K. Nature. 2011 Dec 1;480(7375):34-.

  Read

• Beyond stereospecificity: liquids and mesoscale organization of cytoplasm

  open access

  Hyman AA, Brangwynne CP. Developmental cell. 2011 Jul 19;21(1):14-6.

  Read

• Q&A: Tony Hyman

  interview

  open access

  Hyman T. Tony Hyman. Current Biology. 2011 Apr 12;21(7):R240-2.

  Read

2009

• Growth, fluctuation and switching at microtubule plus ends

  opinion

  review

  Howard J, Hyman AA. Nature Reviews Molecular Cell Biology. 2009 Aug;10(8):569-74.

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  PDF

2007

• Anthony Hyman: From unlikely scientist to Royal Society Fellow

  interview

  open access

  Williams R. The Journal of Cell Biology. 2007 Dec 12;179(7):1330.

  Read

• A pipeline for Europe

  open access

  opinion

  Hyman T, Simons K. Nature. 2007 Sep 13;449(7159):256-.

  Read

• Acto-myosin reorganization and PAR polarity in C. elegans

  review

  Cowan CR, Hyman AA. Development 15 March 2007; 134 (6): 1035-1043.

  Read

  PDF

• Microtubule polymerases and depolymerases

  review

  Howard J, Hyman AA. Current opinion in cell biology. 2007 Feb 1;19(1):31-5.

  Read

  PDF

2006

• Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1

  review

  Kinoshita K, Noetzel TL, Arnal I, Drechsel DN, Hyman AA. Journal of Muscle Research & Cell Motility. 2006 Feb;27:107-14.

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  PDF

2005

• Boveri revisited

  essay

  open access

  Hyman AA. The EMBO Journal. 2005 Mar 23;24(6):1104-10.

  Read

• Cell structure and dynamics

  review

  Hyman AA, Howard J. Current Opinion in Cell Biology. 2005 Feb 1;17(1):1-2.

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2004

• Asymmetric cell division in C. elegans: cortical polarity and spindle positioning

  review

  Cowan CR, Hyman AA. Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. Annu. Rev. Cell Dev. Biol.. 2004 Nov 10;20(1):427-53.

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2003

• Dynamics and mechanics of the microtubule plus end

  review

  Howard J, Hyman AA. Nature. 2003 Apr 17;422(6933):753-8.

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2001

• The spindle: a dynamic assembly of microtubules and motors

  review

  Wittmann T, Hyman A, Desai A. Nature cell biology. 2001 Jan;3(1):E28-34.

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2000

• Centrosomes: Sic transit gloria centri

  open access

  review

  Hyman AA. Current Biology. 2000 Apr 1;10(7):R276-8.

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1996

• No man is an island…

  open access

  Hyman T. Current Biology. 1996 May 1;6(5):491.

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