Hyman Lab News
Suzanne Eaton
We, past and current members of the Hyman lab, are reeling from the sudden and tragic loss of Suzanne Eaton. She was a wonderful person who lives on in our hearts. In this difficult time, we stand together with her family and colleagues.
FlexiBAC, our open source protein expression system
One of great things here at the MPI-CBG are our Service and Facilities, among them the protein expression facility (PEPC), which has been heavily used by us in recent years. In collaboration with Jeff Woodruff, a former postdoc, they developed FlexiBAC, an amazingly versatile protein expression system in insect cells, which was developed with a huge range of different constructs and tags, which might fit your needs as well.
We held the first EMBO phase separation course here at the MPI-CBG
The course was organized together with the Tang and Alberti lab, including morning lectures, theoretical or experimental parts during the day and a relaxing evening part. Importantly, we included as well the project ideas of our participants.
Phase separation buffers noise in cells
In collaboration with the Zechner and Jülicher groups, we now show in theory and experiments that liquid-liquid phase separation (LLPS) can be a very effective mechanism to buffer protein concentrations against gene expression noise.
Rheology of protein condensates using optical traps
Louise and her coworkers now developed a novel method based on optical traps to study the frequency-dependent rheology and the surface tension of P-granule protein PGL-3 condensates as a function of salt concentration.
How do you choose a research topic?
Choosing a research topic is an important decision at any level. The choice shapes decisions about what graduate lab to join, which post-doctoral position to pursue, how to start an independent lab, and what companies might make good employers.