In ALS, a mutated nuclear protein, FUS (fused in sarcoma), mislocalises to the cytoplasm and aggregates in stress granules. This leads to a liquid to solid transition of the granules and a consequent degeneration of the motor neuron (motor neuron die-back ). We show that lipoamide and lipoic acid can prevent the aggregation of FUS and consequently […]
Hyman LabFollow
Science and fun from the lab of Tony Hyman at the MPI-CBG. Tweets by Hymanlab members
Load More...Excited to share our work on sequencing single phase-separated droplets! Huge congrats @dwollny85 for initiating, designing & executing this project!! Thanks to @DoraTang5 and @HymanLab @MariaHondele @melanoidin @GrayCampLab for a great collaboration!!
https://www.nature.com/articles/s41467-022-30158-1Selected Essays
Selected Videos