Posts tagged with science sketches
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New video abstract! Microtubule nucleation through phase separation
Watch our latest video abstract, created by Amayra Hernández-Vega, describing our recent publication in Cell Reports.
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Congratulations to Amayra Hernández-Vega and colleagues on their paper in Cell Reports!
In this work, we show that the protein Tau can phase separate into liquid-like droplets in vitro. These droplets can concentrate tubulin, which enables the polymerization of microtubule bundles that deform the droplets into rod-like structures.
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New video abstract! Building synthetic centrosomes.
Watch our latest video abstract, created by Jeff Woodruff, describing our recent publication in Cell.
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Congratulations to Jeff Woodruff and colleagues on their paper in Cell!
In this work, led by Jeff Woodruff, we used defined components to reconstitute a minimal centrosome in vitro that can nucleate microtubule asters. Our results suggest that the centrosome acts a selective phase that nucleates microtubules by concentrating microtubule polymerases and soluble tubulin.
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ATP as a biological hydrotrope
Congratulations to Avinash, Liliana, and colleagues on their paper in Science, in collaboration with Yamuna Krishnan from UChicago!
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New! Video abstract for "Amyloid-like self-assembly of a cellular compartment"
Watch the video abstract for Boke et al 2016, “Amyloid-like self-assembly of a cellular compartment,” and see the full post about it on the Science Sketches website
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Congratulations to Oliver, Jeff, and colleagues on their paper & video abstract in Biology Open, investigating regulation of centrosome assembly
In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density.
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New publication plus video abstract!
Congratulations to Mark on his paper in Biology Open examining the genetic link between temperature and fertility in nematodes.
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New Two Minute Talk! Elisabeth explains mitotic cell rounding
In the latest addition to our "Two Minute Talk" series, postdoc Elisabeth Fischer-Friedrich explains the biophysics of why and how cells become round during mitosis.