Posts tagged with science-sketches
New video abstract! Microtubule nucleation through phase separation
Watch our latest video abstract, created by Amayra Hernández-Vega, describing our recent publication in Cell Reports.
Congratulations to Amayra Hernández-Vega and colleagues on their paper in Cell Reports!
In this work, we show that the protein Tau can phase separate into liquid-like droplets in vitro. These droplets can concentrate tubulin, which enables the polymerization of microtubule bundles that deform the droplets into rod-like structures.
New video abstract! Building synthetic centrosomes.
Watch our latest video abstract, created by Jeff Woodruff, describing our recent publication in Cell.
Congratulations to Jeff Woodruff and colleagues on their paper in Cell!
In this work, led by Jeff Woodruff, we used defined components to reconstitute a minimal centrosome in vitro that can nucleate microtubule asters. Our results suggest that the centrosome acts a selective phase that nucleates microtubules by concentrating microtubule polymerases and soluble tubulin.
ATP as a biological hydrotrope
Congratulations to Avinash, Liliana, and colleagues on their paper in Science, in collaboration with Yamuna Krishnan from UChicago!
New! Video abstract for "Amyloid-like self-assembly of a cellular compartment"
Watch the video abstract for Boke et al 2016, “Amyloid-like self-assembly of a cellular compartment,” and see the full post about it on the Science Sketches website
Congratulations to Oliver, Jeff, and colleagues on their paper & video abstract in Biology Open, investigating regulation of centrosome assembly
In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density.
New publication plus video abstract!
Congratulations to Mark on his paper in Biology Open examining the genetic link between temperature and fertility in nematodes.
New Two Minute Talk! Elisabeth explains mitotic cell rounding
In the latest addition to our "Two Minute Talk" series, postdoc Elisabeth Fischer-Friedrich explains the biophysics of why and how cells become round during mitosis.