Hyman Lab News
Molecular biology: A liquid reservoir for silent chromatin
Tony and our postdoc Adam Klosin have written a Nature “News & Views” about chromatin compaction in liquid droplets based on two articles in the latest issue of Nature (Strom et al & Larson et al).
Congratulations to Jeff Woodruff and colleagues on their paper in Cell!
In this work, led by Jeff Woodruff, we used defined components to reconstitute a minimal centrosome in vitro that can nucleate microtubule asters. Our results suggest that the centrosome acts a selective phase that nucleates microtubules by concentrating microtubule polymerases and soluble tubulin.
Stem cells: the new "model organism"
In a new perspective published in Molecular Biology of the Cell, Tony Hyman and David Drubin “argue that combined advances in genome editing, stem cell production, and organoid derivation from stem cells represent a revolution in cell biology.”
PNAS Journal Club, ACS Spotlights, & Press for "ATP as a biological hydrotrope"
Our article “ATP as a biological hydrotrope” is featured this month as a Journal Club highlight in PNAS! Additionally, ACS Chemical Biology covered the article in its Spotlights section.
Two preprints: Tau phase separation; Parallel temperature adaptation
The Hyman lab is proud to publish preprints, which we post in parallel to journal submission. You can find our latest manuscripts on bioRxiv, and we welcome your feedback.
Interview with Kate Lee in 'Research in Germany'
You can now read an interview with our postdoc Kate Lee in “Research in Germany”, where she discusses her work on phase transitions and neurodegenerative disease, her decision to move to Europe, and what she enjoys most about working at the MPI-CBG.