Our article “ATP as a biological hydrotrope” is featured this month as a Journal Club highlight in PNAS! Additionally, ACS Chemical Biology covered the article in its Spotlights section. It has also been featured in the following news articles and press releases: • Chemical & Engineering News • MPI-CBG Press Release (also in German) • C2W […]
The Hyman lab is proud to publish preprints, which we post in parallel to journal submission. You can find our latest manuscripts on bioRxiv, and we welcome your feedback: Local Nucleation Of Microtubule Bundles Through Tubulin Concentration Into A Condensed Tau Phase. Amayra Hernández-Vega, Marcus Braun, Lara Scharrel, Marcus Jahnel, Susanne Wegmann, Bradley T. Hyman, Simon […]
You can now read an interview with our postdoc Kate Lee in “Research in Germany”, where she discusses her work on phase transitions and neurodegenerative disease, her decision to move to Europe, and what she enjoys most about working at the MPI-CBG. Congrats, Kate!
New work from the Hyman and Alberti labs uncovers an important role for chaperone proteins in preventing aberrant phase transitions in stress granules. See a brief synopsis below and read the full paper online. Congratulations to all of the authors on this work! Synopsis The presence of misfolded protein in stress granules alters their dynamic state […]
Our latest publication, in collaboration with Yamuna Krishnan in Chicago, is out today in Science! In this work, we show that ATP can act as a biological hydrotrope, keeping proteins soluble. Hydrotropes are amphiphilic small molecules that solubilize hydrophobic molecules in aqueous solutions. While ATP is most commonly known as the energy source for cells, there […]
