In new work published this month in Biology Open, Oliver Wueseke, David Zwicker, Jeff Woodruff, and colleagues show that PKL-1 phosphorylation of the centrosome scaffold protein SPD-5 is a key regulatory step which determines centrosome size and density. Importantly, they show that this step is not necessary for proper maintenance or function of the centrosome. […]
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Load More...bioRxiv@biorxivpreprintEver wonder how cellular condensates contribute to function? Can condensates deliver robust functional output in spite of changing conditions- short-term effects of chemical modifications, intrinsic mutational changes, accumulation of high local concentration of sticky molecules? https://twitter.com/biorxivpreprint/status/1526359522058682369
Composition can buffer protein dynamics within liquid-like condensates. https://biorxiv.org/cgi/content/short/2022.05.16.492059v1 #bioRxiv
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