Hyman Lab News
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Happy New Year from the Hyman Lab!
Wishing you all the best for 2014 with artwork by our very own Julia Eichhorn.
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Countdown to ASCB
From December 14-18, cell biologists from around the world will converge on New Orleans to meet and share their latest research and ideas. Tony will be there chairing a session, and our postdoc Kate Lee is presenting a poster.
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We support eLife!
An interesting and provocative article by Nobel laureate Randy Schekman was published in The Guardian yesterday. Randy detailed some of the problems created by the pressure to publish in “luxury”, high-profile, subscription-based journals.
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Upcoming talk: Physics of Biology Conference
Tony will be giving a talk at the upcoming Physics of Biology Conference in Geneva. If you'll be at the meeting, you can catch Tony's talk at 12:30 on Wednesday, November 27!
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New publication: Spatial organization of the cell cytoplasm by position-dependent phase separation.
During asymmetric cell division, cytoplasmic components are segregated to opposite sides of the cell. We discuss how the observed segregation can be achieved by a position-dependent phase separation mechanism controlled by a protein concentration gradient. We show that effects of even a weak gradient can be amplified by the phase transition to achieve strong segregation. We compare our theory to the segregation of germ granules observed during the divisions in the C. elegans embryo. Our study demonstrates how liquid-liquid phase separation can play a key role in the organization of the cytoplasm.