The Hyman and Zechner labs are looking for a PhD student to research the control of cellular noise via phase separation.
Brief summary:
Liquid condensates provide a potential mechanism to control molecular fluctuations in cells. We have recently provided a first proof of principle of this idea using theory and single-cell experiments. In this project, we want to explore this concept more broadly within physiological contexts and understand its functional implications for cellular control. The project has a highly interdisciplinary character and bridges between experimental work and theory. We welcome both theorists and experimentalists to apply.
Qualifications of the candidate:
Biophysics, biochemistry, single-cell biology, theoretical physics, stochastic processes.
Relavent Publications:
- Klosin, A.*, Oltsch, F. *, Julicher, F., Harmon, T., Honigmann, A., Hyman, A.A., Zechner, C. (2020). Phase separation provides a mechanism to reduce noise in cells. Science 367, 464-467. *(co-first authors)