In a new perspective published in Molecular Biology of the Cell, Tony Hyman and David Drubin “argue that combined advances in genome editing, stem cell production, and organoid derivation from stem cells represent a revolution in cell biology.” These technological advances mean that stem cell studies could now replace molecular and cell biology studies traditionally carried out in human tissue culture cells, which have significant genome abnormalities and do not represent a normal physiological state. Read more in the full article in MBOC.
Stem cells: the new “model organism” David G. Drubin and Anthony A. Hyman. Mol Biol Cell, 2017. 28(11)1409-1411.