Congratulations to Marco Hein, Nina Hubner, our own Ina Poser, and colleagues on their new publication in Cell, “A human interactome in three quantitative dimensions organized by stoichiometries and abundances.” This is a truly impressive body of work which globally analyzes protein interactions in order to better understand protein networks and cell organization. This dataset connects 5,400 proteins with 28,500 interactions and shows that weak interactions dominate the protein network.
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M. Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.